Arizona psychologist sees some benefit to study of illegal drug that helps PTSD

PHOENIX — Clinical trials are starting soon for an illegal drug that’s been shown to help ease symptoms of post-traumatic stress disorder.

MDMA – better known as “Ecstasy” – was combined with psychotherapy in several recent studies. Data showed 83 percent of participants were symptom-free within two months. A follow-up four years later found that effect stuck.

The FDA gave approval for Phase-3 clinical trials for Ecstasy in late November. The trials will include a pure form of MDMA as well as psychotherapy.

Scottsdale psychologist Dr. Sanford Silverman said the psychotherapy is a vital part of PTSD treatment. “When we help … the brain to reorganize itself,” he said, “then you are in a much better neurological, and mental and emotional state.”

The Multidisciplinary Association for Psychedelic Studies, a small nonprofit created in 1985, conducted the recent studies, treating 130 patients with Ecstasy.

The nonprofit is also funding the Phase-3 research. That will include at least 230 patients.

Silverman said medications for PTSD do help. The FDA has approved two.

However, Silverman said, “When you take a drug, you don’t know how long it’s going to last. And it’s an external agent impacting upon you.”

Phase-3 clinical trials are the final step before possible FDA approval of prescription medications.

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