EU regulator recommends clearing Takeda’s dengue vaccine

Oct 14, 2022, 5:05 AM | Updated: 5:21 am
FILE - In this Jan. 27, 2016, file photo, an Aedes aegypti mosquito known to carry the Zika virus a...

FILE - In this Jan. 27, 2016, file photo, an Aedes aegypti mosquito known to carry the Zika virus and the Dengue fever, is photographed through a microscope at the Fiocruz institute in Recife, Pernambuco state, Brazil. In a statement on Friday, Oct. 14, 2022, the European Medicines Agency is recommending that a dengue vaccine made by the Japanese pharmaceutical Takeda be authorized, in a move that could provide a new tool for millions worldwide against the potentially fatal disease. (AP Photo/Felipe Dana, File)

(AP Photo/Felipe Dana, File)

LONDON (AP) — The European Medicines Agency on Friday recommended the authorization of a dengue vaccine made by the Japanese pharmaceutical Takeda that could provide a new tool for millions worldwide against the potentially fatal disease.

The EU regulator said in a statement the vaccine should be cleared for anyone aged four and over, to prevent the four types of dengue. The viral disease causes more than 390 million infections globally every year, including up to 25,000 deaths, mostly in children.

“The benefits and safety of the current vaccine have been evaluated in 19 clinical trials that enrolled more than 27,000 people aged between 15 months and 60 years,” the EMA said. Studies showed Takeda’s vaccine was about 84% effective in preventing people from being hospitalized with dengue and about 61% effective in stopping symptoms four years after getting immunized.

The most commonly reported side effects included headaches and muscle pain.

There is no specific treatment for dengue, which is a leading cause of serious illness and death in roughly 120 Latin American and Asian countries. While about 80% of infections are mild, severe cases of the mosquito-spread disease can lead to internal bleeding, organ damage and death.

The green light for the Takeda vaccine comes after Sanofi Pasteur’s dengue vaccine triggered a public health crisis in the Philippines in 2017. The Dengvaxia shot was found to increase the risk of severe disease in people who had not previously been infected with dengue and was linked to the deaths of more than 100 children.

Critics charged that the Sanofi vaccine was rolled out prematurely to about 800,000 children across the Philippines. Numerous scientists and officials were indicted for introducing the vaccine “with undue haste,” that prosecutors said resulted in homicide.

The World Health Organization had previously concluded the Sanofi Pasteur vaccine was safe, but later said children should only be immunized if they were tested first to ensure they had already had dengue.

The EMA said its endorsement of the Takeda vaccine means that “a global unmet public health need is being addressed,” explaining that countries beyond the EU should have confidence that the shot is safe and effective.

After malaria, dengue is the most diagnosed cause of fever in European travelers returning from developing countries.

In September, Indonesia became the first country to license the Takeda vaccine.

Copyright © The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

AP

Secretary of Defense Lloyd Austin introduces the B-21 Raider stealth at Northrop Grumman Friday, De...
Associated Press

Keep COVID military vaccine mandate, defense chief says

ABOARD A U.S. MILITARY AIRCRAFT (AP) — Defense Secretary Lloyd Austin said he wants to keep the military’s COVID-19 vaccine mandate in place to protect the health of the troops, as Republican governors and lawmakers press to rescind it. This past week more than 20 Republican governors sent a letter to President Joe Biden asking […]
19 hours ago
Associated Press

Family says coyote attacked toddler outside LA home

LOS ANGELES (AP) — A coyote ambushed and injured a 2-year old girl outside her Los Angeles home in a daytime attack before her father chased the animal off, her family said. Home security video obtained by KTLA-TV shows the animal grab and drag the toddler across her lawn and sidewalk, just seconds after her […]
19 hours ago
FILE -  Rep. Jim Kolbe, R-Ariz, speaks during a press conference at the American University of Beir...
Associated Press

Longtime Arizona GOP Rep. Jim Kolbe dies at 80

PHOENIX (AP) — Jim Kolbe, a Republican congressman who represented a heavily Democratic region of Arizona for more than two decades and was a proponent of gay rights, has died. He was 80. Arizona Gov. Doug Ducey said in a statement that Kolbe died Saturday. Ducey ordered flags lowered until sunset Sunday. Kolbe served in […]
19 hours ago
Associated Press

Fan buying famed ‘Goonies’ house in Oregon, listed for $1.7M

ASTORIA, Ore. (AP) — The listing agent for the Victorian home featured in the “The Goonies” film in Astoria, Oregon, said this week the likely new owner is a fan of the classic coming-of-age movie about friendships and treasure hunting, and he promises to preserve and protect the landmark. The 1896 home with sweeping views […]
19 hours ago
New Los Angeles County Sheriff Robert Luna is sworn in by the Honorable Samantha Jersey, Presiding ...
Associated Press

New LA sheriff vows accountability, integrity for department

LOS ANGELES (AP) — The new head of the nation’s largest sheriff’s department vowed Saturday to usher in an era of integrity and collaboration after his predecessor’s tenure was marked by clashes with other public officials and allegations that ganglike groups of deputies ran amok within the agency. Robert Luna took an oath of office […]
19 hours ago
A a fan waits for the start of the World Cup round of 16 soccer match between the Netherlands and t...
Associated Press

American fans captivated by US team’s World Cup run

AL RAYYAN, Qatar (AP) — The bald man came dressed head-to-toe in full American spirit. A red, white and blue bandana, stars and stripes mismatched socks, shorts that might have been swimming trunks suited for a summer barbeque. Philip Labas wore an outfit bursting with pride for the United States men’s soccer team Saturday as […]
19 hours ago

Sponsored Articles

...
Day & Night Air Conditioning, Heating and Plumbing

Prep the plumbing in your home just in time for the holidays

With the holidays approaching, it's important to know when your home is in need of heating and plumbing updates before more guests start to come around.
...
Quantum Fiber

Stream 4K and more with powerful, high-speed fiber internet

Picking which streaming services to subscribe to are difficult choices, and there is no room for internet that cannot handle increased demands.
...
Day & Night Air Conditioning, Heating and Plumbing

Here are 4 signs the HVAC unit needs to be replaced

Pool renovations and kitchen upgrades may seem enticing, but at the forefront of these investments arguably should be what residents use the most. In a state where summertime is sweltering, access to a functioning HVAC unit can be critical.
EU regulator recommends clearing Takeda’s dengue vaccine