UNITED STATES NEWS

US expected to authorize mix-and-match COVID booster shots

Oct 19, 2021, 10:10 AM | Updated: Oct 20, 2021, 10:33 am
FILE - This Dec. 23, 2020 file photo shows a vial of the Moderna COVID-19 vaccine in the first roun...

FILE - This Dec. 23, 2020 file photo shows a vial of the Moderna COVID-19 vaccine in the first round of staff vaccinations at a hospital in Denver. Federal regulators are expected to authorize the mixing and matching of COVID-19 booster shots this week in an effort to provide flexibility for those seeking to maintain protection against the coronavirus. The upcoming announcement by the Food and Drug Administration is likely to come along with authorization for boosters of the Moderna and Johnson & Johnson shots. (AP Photo/David Zalubowski, File)

(AP Photo/David Zalubowski, File)

WASHINGTON (AP) — Federal regulators are expected to authorize the mixing and matching of COVID-19 booster doses this week in an effort to provide flexibility as the campaign for extra shots expands.

The upcoming announcement by the Food and Drug Administration is likely to come along with authorization for boosters of the Moderna and Johnson & Johnson shots and follows the OK for a third dose for the Pfizer vaccine for many Americans last month. The move was previewed Tuesday by a U.S. health official familiar with the matter who was not authorized to speak publicly ahead of the announcement.

The FDA was expected to say that using the same brand for a booster was still preferable, especially for the mRNA vaccines from Pfizer and Moderna that have proved most effective against the coronavirus. The agency was still finalizing guidance for the single-shot J&J vaccine.

Preliminary results from a government study of different booster combinations found an extra dose of any type revs up levels of virus-fighting antibodies regardless of the brand people first received. But recipients of the single-dose J&J vaccination had the most dramatic response — a 76-fold and 35-fold jump in antibody levels, respectively, shortly after either a Moderna or Pfizer booster, compared to a four-fold rise after a second J&J shot.

One confusing decision is what Moderna dose to recommend in combination with other brands. Moderna has applied for its booster to be half the original dose, saying that’s plenty for people who already received two full-strength shots. But the mix-and-match study used full-strength extra doses, and there’s no way to know if a half-dose Moderna booster would trigger as strong a reaction in J&J recipients.

Allowing mixing and matching could make the task of getting a booster simpler for Americans and allow people who may have had adverse reactions to the initial dose to try a different shot.

Last week, the U.S. said it would recognize combinations of vaccines administered overseas for the purposes of entering the country. The practice was common in Canada and some European countries in the early months of the vaccination campaign..

___

AP Medical Writer Lauran Neergaard contributed.

Copyright © The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

United States News

FILE - A passenger uses a laptop aboard a commercial airline flight from Boston to Atlanta on July ...
Associated Press

FAA clears Verizon and AT&T to turn on more 5G cell towers

Federal safety regulators say they have cleared the way for Verizon and AT&T to power up more towers for new 5G service without causing radio interference with airplanes. The Federal Aviation Administration said Friday that it took the steps after receiving details from the telecommunications companies about the location of wireless transmitters. The FAA’s move […]
20 hours ago
Associated Press

Wayne Stenehjem, ND’s longest-serving attorney general, dies

BISMARCK, N.D. (AP) — North Dakota Attorney General Wayne Stenehjem has died at age 68, his office announced Friday, shortly after he was hospitalized for what his brother said was an inflamed ulcer. Stenehjem died about 6:20 p.m. at a Bismarck hospital, his spokeswoman Liz Brocker said. She said she could not provide additional details. […]
20 hours ago
Associated Press

Some Vegas Strip casinos to get new facades, familiar names

LAS VEGAS (AP) — Some shuffling among owners could result in rebranding, demolition, reconstruction and the addition of familiar names at some of the Las Vegas Strip’s most iconic properties. Caesars Entertainment Inc., owner of the venerable Bally’s Las Vegas, announced this week that it plans to rename its heart-of-the-Strip towers the Horseshoe Las Vegas, […]
20 hours ago
Associated Press

4 killed, including 2 children, in Arkansas house fire

HOT SPRINGS, Ark. (AP) — Flames engulfed a house in central Arkansas on Friday, killing four people, including two children, officials said. The fire was reported shortly after 10 a.m., Arkansas State Police said in a statement. First responders arrived to find the home, located about 3 miles (5 kilometers) northeast of Hot Springs, fully […]
20 hours ago
Associated Press

Prosecutors: Felon fired BB gun at Planned Parenthood clinic

LOS ANGELES (AP) — A convicted felon suspected of firing a BB gun at a Planned Parenthood clinic in California on multiple occasions was arrested Friday on a federal firearms charge. Richard Chamberlin, 53, had a loaded .22 caliber semi-automatic handgun in his car when he was stopped after one of several drive-by shooting attacks […]
20 hours ago
A man walks in front of a billboard for Egyptian President Egyptian President Abdel-Fattah el-Sissi...
Associated Press

US halts Egypt military aid over rights after huge arms sale

WASHINGTON (AP) — The Biden administration said Friday it is cancelling $130 million in military aid to Egypt over human rights concerns. The announcement comes just days after the administration approved a massive $2.5 billion arms sale to the country. The State Department said Friday that Egypt had not met the conditions to receive the […]
20 hours ago

Sponsored Articles

GLENDALE, AZ - DECEMBER 27: Wide receivers John Brown #12 and Larry Fitzgerald #11 of the Arizona C...
Arizona Department of Gaming

The most memorable games in Arizona sports history every fan needs to know

Sports teams in Arizona have seen their fair share of instant classic games, but there's a few that every fan needs to know.
...
Sanderson Ford

Sanderson Ford offers cars and deals for all this holiday season

Sanderson Ford’s No! Vember Black Friday sale is giving an opportunity to purchase a new 2021 vehicle just in time for the holiday season.
(Facebook Photo/NHTSA)...
Sweet James

Upcoming holiday season is peak time for DUI arrests

The holiday season may be the most wonderful time of the year, but it’s also the most dangerous time of the year to be driving. That’s why it’s important to remember to call Sweet James Accident Attorneys if you’re injured or arrested because of a DUI accident.
US expected to authorize mix-and-match COVID booster shots